Evidence · Peer-reviewed
Don't just take our word for it
Researchers around the world have studied how freeze-drying affects human milk since the 1950s. Milk banks and hospitals use the technique today to preserve the nutrition and bioactives in donor milk. This is that body of work, collected in one place.
Showing 38 of 38 studies
Nutrients
15Fats, proteins, vitamins and trace elements — how each survives freeze-drying, and how storage time affects them.
Immune Factors
5Immunoglobulins, lysozyme, lactoferrin and cytokines — the immune-active proteins in milk, and how much of each survives processing.
Probiotics/Pre-biotics (HMOs)
6Live cultures, human milk oligosaccharides and glycoproteins — the probiotic and prebiotic components that seed and feed an infant's developing gut.
Clinical Studies
4Freeze-dried human milk used with real infants — fortification, tolerance and growth outcomes in preterm and medically complex babies.
Microbial Safety
4Bacterial safety and the milk's own antibacterial activity — what freeze-drying does to both, next to pasteurization and irradiation.
Historical Studies
4The original mid-century work establishing that human milk could be freeze-dried and stored — some of it seventy years old.
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This library collects published research on freeze-drying human milk. Most of these studies are independent of Milkify and describe freeze-drying in general rather than Milkify's SafeDry™ process specifically. The 2026 case report in AJP Reports is an exception: it describes an infant fed milk processed with SafeDry™ and was co-authored by Milkify staff. Last reviewed July 2026.